Effects of hematoporphyrin (HPD) and a chemiluminescence system on the growth of transplanted tumors in C3H/HeJ mice.

نویسندگان

  • M J Phillip
  • J D McMahon
  • M D O'Hara
  • F W Hetzel
  • C Amsterdamsky
  • A P Schaap
چکیده

Photoradiation therapy is emerging as a promising technique for combating cancer. Fundamentally, this approach consists of two steps: hematoporphyrin derivative (HPD) is used to selectively sensitize cancer cells to visible light; after an appropriate time interval, light is introduced into the tumor via a laser-fiber optic system to trigger the cytotoxic action of HPD. The present investigation was initiated to determine the therapeutic potential of HPD in combination with a chemiluminescent activator in treating mice which had been transplanted with tumors.

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عنوان ژورنال:
  • Progress in clinical and biological research

دوره 170  شماره 

صفحات  -

تاریخ انتشار 1984